Post by Lyme Challenged on Dec 22, 2015 19:20:14 GMT -5
Compliments of Thomas Grier
Borrelia burgdorferi was found in the spinal fluid of a Norwegian MS patient using our DNA Beacon Probes.
Here a group of B burgdorferi are found clumping together in a thin biofilm. Finding this in spinal fluid is a huge discovery!
We are finding that Borrelia miyamotoi is extremely neurogenic and a source of neurologic morbidity in both Alzheimer like dementia and MS. This slide is from the same Norwegian MS patient.
There is great beauty in the elegance of this work. Not to appreciate it or acknowledge it will cause tens of thousands of patients to suffer needlessly. Help fund our work and enlist other scientists to see for themselve that Borrelia connection to MS and dementia.
A slightly different DNA beacon and fluorescent stain, but the result is the same. B miyamotoi is found in the CSF of this MS patients. We need funding to test a 1000 more CSFs.
Thomas Grier added 5 new photos.
1 hr ยท
These latest slides from Alan MacDonald are from a Norwegian MS patient. They were created by simply placing a drop of the patient's spinal fluid on a glass slide, and applying the FISH Stain DNA Beacons.
The slides are beautiful and give us hope that less invasive methods than brain biopsy can be successful at detecting Borrelia Infections in Neurological Illnesses like Multiple Sclerosis.
Two different species of Borrelia were detected in this patient: Borrelia burgdorferi (Lyme disease) and Borrelia miyamotoi (Tick Borne relapsing Fever)
Notice that even in the CSF a thin biofilm of Borrelia can be detected.
Although two species of Borrelia were detected, other neurogenic species like B valaisianna cannot be detected because we lack the proper DNA beacons to detect any other species. We suspect other Borrelia species are also invading the brain and persist but we do not yet have the tools to detect the other half dozen potential Borrelia neurogenic species.
It only costs about $2,000 to develop each stain. Please contribute to the Paul H Duray Pathology fund to help us create these needed stains!
If you are looking at these slides and not saying: WOW! then you are not grasping the implications of this case.
This one case suggests we now have a tool to detect those MS patients that are misdiagnosed with MS and actually have a treatable Borrelia infection of the brain.
This case means that spinal fluid (CSF) may be useful in the diagnosis of neuroborreliosis. This is far less invasive than a brain biopsy. It means not all MS patients need to go on immuno-suppressive drugs. Antibiotics may one day be a valid and accepted treatment for suspicious cases of Multiple Sclerosis that involve Borrelia infections of the brain.
Please help support our research. You can find a link to our fund on Alan MacDonald's page. We desperately need DNA beacon stains for all neurogenic strains of Borrelia !
All donations are tax deductible. We are a 501c3b non-profit corp
www.gofundme.com/z3v2a2k
Borrelia burgdorferi was found in the spinal fluid of a Norwegian MS patient using our DNA Beacon Probes.
Here a group of B burgdorferi are found clumping together in a thin biofilm. Finding this in spinal fluid is a huge discovery!
We are finding that Borrelia miyamotoi is extremely neurogenic and a source of neurologic morbidity in both Alzheimer like dementia and MS. This slide is from the same Norwegian MS patient.
There is great beauty in the elegance of this work. Not to appreciate it or acknowledge it will cause tens of thousands of patients to suffer needlessly. Help fund our work and enlist other scientists to see for themselve that Borrelia connection to MS and dementia.
A slightly different DNA beacon and fluorescent stain, but the result is the same. B miyamotoi is found in the CSF of this MS patients. We need funding to test a 1000 more CSFs.
Thomas Grier added 5 new photos.
1 hr ยท
These latest slides from Alan MacDonald are from a Norwegian MS patient. They were created by simply placing a drop of the patient's spinal fluid on a glass slide, and applying the FISH Stain DNA Beacons.
The slides are beautiful and give us hope that less invasive methods than brain biopsy can be successful at detecting Borrelia Infections in Neurological Illnesses like Multiple Sclerosis.
Two different species of Borrelia were detected in this patient: Borrelia burgdorferi (Lyme disease) and Borrelia miyamotoi (Tick Borne relapsing Fever)
Notice that even in the CSF a thin biofilm of Borrelia can be detected.
Although two species of Borrelia were detected, other neurogenic species like B valaisianna cannot be detected because we lack the proper DNA beacons to detect any other species. We suspect other Borrelia species are also invading the brain and persist but we do not yet have the tools to detect the other half dozen potential Borrelia neurogenic species.
It only costs about $2,000 to develop each stain. Please contribute to the Paul H Duray Pathology fund to help us create these needed stains!
If you are looking at these slides and not saying: WOW! then you are not grasping the implications of this case.
This one case suggests we now have a tool to detect those MS patients that are misdiagnosed with MS and actually have a treatable Borrelia infection of the brain.
This case means that spinal fluid (CSF) may be useful in the diagnosis of neuroborreliosis. This is far less invasive than a brain biopsy. It means not all MS patients need to go on immuno-suppressive drugs. Antibiotics may one day be a valid and accepted treatment for suspicious cases of Multiple Sclerosis that involve Borrelia infections of the brain.
Please help support our research. You can find a link to our fund on Alan MacDonald's page. We desperately need DNA beacon stains for all neurogenic strains of Borrelia !
All donations are tax deductible. We are a 501c3b non-profit corp
www.gofundme.com/z3v2a2k